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Investigation of Indolglyoxamide and Indolacetamide Analogues of Polyamines as Antimalarial and Antitrypanosomal Agents

Pure compound screening has previously identified the indolglyoxylamidospermidine ascidian metabolites didemnidine A and B (2 and 3) to be weak growth inhibitors of Trypanosoma brucei rhodesiense (IC(50) 59 and 44 μM, respectively) and Plasmodium falciparum (K1 dual drug resistant strain) (IC(50) 41...

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Sonraí Bibleagrafaíochta
Main Authors: Wang, Jiayi, Kaiser, Marcel, Copp, Brent R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071569/
https://ncbi.nlm.nih.gov/pubmed/24879541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md12063138
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