טוען...
CTLA4 aptamer delivers STAT3 siRNA to tumor-associated and malignant T cells
Intracellular therapeutic targets that define tumor immunosuppression in both tumor cells and T cells remain intractable. Here, we have shown that administration of a covalently linked siRNA to an aptamer (apt) that selectively binds cytotoxic T lymphocyte–associated antigen 4 (CTLA4(apt)) allows ge...
שמור ב:
| Main Authors: | , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Clinical Investigation
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4071407/ https://ncbi.nlm.nih.gov/pubmed/24892807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73174 |
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