Chronic Treatment with Anesthetic Propofol Improves Cognitive Function and Attenuates Caspase Activation in Both Aged and Alzheimer's Disease Transgenic Mice

There is a need to seek new treatment(s) for Alzheimer's disease (AD). A recent study showed that AD patients may have decreased levels of functional GABA receptors. Propofol, a commonly used anesthetic, is a GABA receptor agonist. We therefore set out to perform a proof of concept study to det...

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Hlavní autoři: Shao, Haijun, Zhang, Yiying, Dong, Yuanlin, Yu, Buwei, Xia, Weiming, Xie, Zhongcong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071129/
https://ncbi.nlm.nih.gov/pubmed/24643139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-132792
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