Dynamic imbalance between cancer cell subpopulations induced by Transforming Growth Factor Beta (TGF-β) is associated with a DNA methylome switch

BACKGROUND: Distinct subpopulations of neoplastic cells within tumors, including hepatocellular carcinoma (HCC), display pronounced ability to initiate new tumors and induce metastasis. Recent evidence suggests that signals from transforming growth factor beta (TGF-β) may increase the survival of th...

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Detalhes bibliográficos
Main Authors: Martin, Marion, Ancey, Pierre-Benoit, Cros, Marie-Pierre, Durand, Geoffroy, Le Calvez-Kelm, Florence, Hernandez-Vargas, Hector, Herceg, Zdenko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070873/
https://ncbi.nlm.nih.gov/pubmed/24898317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-435
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