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Dynamic imbalance between cancer cell subpopulations induced by Transforming Growth Factor Beta (TGF-β) is associated with a DNA methylome switch

BACKGROUND: Distinct subpopulations of neoplastic cells within tumors, including hepatocellular carcinoma (HCC), display pronounced ability to initiate new tumors and induce metastasis. Recent evidence suggests that signals from transforming growth factor beta (TGF-β) may increase the survival of th...

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Détails bibliographiques
Auteurs principaux: Martin, Marion, Ancey, Pierre-Benoit, Cros, Marie-Pierre, Durand, Geoffroy, Le Calvez-Kelm, Florence, Hernandez-Vargas, Hector, Herceg, Zdenko
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070873/
https://ncbi.nlm.nih.gov/pubmed/24898317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-435
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