Dynamic imbalance between cancer cell subpopulations induced by Transforming Growth Factor Beta (TGF-β) is associated with a DNA methylome switch

BACKGROUND: Distinct subpopulations of neoplastic cells within tumors, including hepatocellular carcinoma (HCC), display pronounced ability to initiate new tumors and induce metastasis. Recent evidence suggests that signals from transforming growth factor beta (TGF-β) may increase the survival of th...

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Autori principali: Martin, Marion, Ancey, Pierre-Benoit, Cros, Marie-Pierre, Durand, Geoffroy, Le Calvez-Kelm, Florence, Hernandez-Vargas, Hector, Herceg, Zdenko
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070873/
https://ncbi.nlm.nih.gov/pubmed/24898317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-435
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