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Dysregulation of ubiquitin-proteasome pathway and apolipoprotein A metabolism in sickle cell disease–related pulmonary arterial hypertension
Abstract. Pulmonary arterial hypertension (PAH) is a major complication of sickle cell disease (SCD). Low levels of apolipoprotein A1 (Apo-A1) have been implicated in the development of PAH in SCD. We speculate that lower levels of Apo-A1 are related to dysregulation of the ubiquitin-proteasome path...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
University of Chicago Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4070832/ https://ncbi.nlm.nih.gov/pubmed/25006400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/674763 |
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