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Ubiquitin-Proteasome System Profiling in Acute Leukemias and its Clinical Relevance
The ubiquitin-proteasome system (UPS) plays a major role in the homeostasis of cellular protein. We demonstrate that each of the major hematologic diseases (AML, ALL, and MDS) has a specific and different plasma profile of UPS protein and enzymatic activities. While high levels of proteasome and ubi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4051750/ https://ncbi.nlm.nih.gov/pubmed/20951430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2010.09.009 |
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