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Transient but not genetic loss of miR-451 is protective in the development of pulmonary arterial hypertension

Abstract. MicroRNAs are small noncoding RNAs involved in the regulation of gene expression and have recently been implicated in the development of pulmonary arterial hypertension (PAH). Previous work has established that miR-451 is upregulated in rodent models of PAH. The role of miR-451 in the pulm...

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Detalhes bibliográficos
Main Authors: Grant, Jennifer S., Morecroft, Ian, Dempsie, Yvonne, van Rooij, Eva, MacLean, Margaret R., Baker, Andrew H.
Formato: Artigo
Idioma:Inglês
Publicado em: University of Chicago Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070830/
https://ncbi.nlm.nih.gov/pubmed/25006399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/674751
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