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Transient but not genetic loss of miR-451 is protective in the development of pulmonary arterial hypertension

Abstract. MicroRNAs are small noncoding RNAs involved in the regulation of gene expression and have recently been implicated in the development of pulmonary arterial hypertension (PAH). Previous work has established that miR-451 is upregulated in rodent models of PAH. The role of miR-451 in the pulm...

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Hlavní autoři: Grant, Jennifer S., Morecroft, Ian, Dempsie, Yvonne, van Rooij, Eva, MacLean, Margaret R., Baker, Andrew H.
Médium: Artigo
Jazyk:Inglês
Vydáno: University of Chicago Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070830/
https://ncbi.nlm.nih.gov/pubmed/25006399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/674751
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