Biochemical Evidence that Human EB1 Does not Bind Preferentially to the Microtubule Seam

EB1 is a highly conserved microtubule (MT) plus end tracking protein (+TIP) involved in regulating MT dynamics, but the mechanisms of its effects on MT polymerization remain undefined. Resolving this question requires understanding how EB1 interacts with MTs. Previous electron microscopy of the S. p...

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Main Authors: Alberico, Emily O., Lyons, Daniel F., Murphy, Ryan J., Philip, Julia T., Duan, Aranda R., Correia, John J., Goodson, Holly V.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070737/
https://ncbi.nlm.nih.gov/pubmed/23864329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.21108
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