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Eugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses

Eugenol and carvacrol from clove and oregano, respectively, are agonists of the warmth-sensitive transient receptor potential channel TRPV3 and the irritant-sensitive TRPA1. Eugenol and carvacrol induce oral irritation that rapidly desensitizes, accompanied by brief enhancement of innocuous warmth a...

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Bibliografiske detaljer
Main Authors: Klein, Amanda H., Joe, Christopher L., Davoodi, Auva, Takechi, Kenichi, Carstens, Mirela Iodi, Carstens, E
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070529/
https://ncbi.nlm.nih.gov/pubmed/24759772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.04.019
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