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Eugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses
Eugenol and carvacrol from clove and oregano, respectively, are agonists of the warmth-sensitive transient receptor potential channel TRPV3 and the irritant-sensitive TRPA1. Eugenol and carvacrol induce oral irritation that rapidly desensitizes, accompanied by brief enhancement of innocuous warmth a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4070529/ https://ncbi.nlm.nih.gov/pubmed/24759772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.04.019 |
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