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Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from mitochondria to the ER in cancer cells

BACKGROUND: Resistance to cell death in the presence of stressful stimuli is one of the hallmarks of cancer cells acquired during multistep tumorigenesis, and knowledge of the molecular mechanism of stress adaptation can be exploited to develop cancer-selective therapeutics. Mitochondria and the end...

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Bibliografiske detaljer
Main Authors: Park, Hye-Kyung, Lee, Ji-Eun, Lim, Jaehwa, Kang, Byoung Heon
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070406/
https://ncbi.nlm.nih.gov/pubmed/24924916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-148
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