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Heterologous Expression and Manipulation of Three Tetracycline Biosynthetic Pathways()

[Image: see text] Three and one: Three tetracycline biosynthetic pathways have been overexpressed and manipulated in heterologous host Streptomyces lividans K4-114. New tetracycline modifying enzymes have been identified through a series of gene inactivation and intermediate characterization. The co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Peng, Kim, Woncheol, Pickens, Lauren B., Gao, Xue, Tang, Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070387/
https://ncbi.nlm.nih.gov/pubmed/23024027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201205426
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