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Biochemical Analysis of the Biosynthetic Pathway of an Anticancer Tetracycline SF2575
SF2575 1 is a tetracycline polyketide produced by Streptomyces sp. SF2575 and displays exceptionally potent anticancer activity towards a broad range of cancer cell lines. The structure of SF2575 is characterized by a highly substituted tetracycline aglycon. The modifications include methylation of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2800175/ https://ncbi.nlm.nih.gov/pubmed/19908837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja907852c |
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