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Elucidation of Pseurotin Biosynthetic Pathway Points to Trans-Acting C-Methyltransferase and Source of Chemical Diversity Generation

Pseurotins comprise a family of structurally related Aspergillal natural products having interesting bioactivity. However, little is known about the biosynthetic steps involved in the formation of their complex chemical features. Here, we systematically deleted the pseurotin biosynthetic genes in A....

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Tsunematsu, Yuta, Fukutomi, Manami, Saruwatari, Takayoshi, Noguchi, Hiroshi, Watanabe, Kenji, Hotta, Kinya, Tang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605568/
https://ncbi.nlm.nih.gov/pubmed/24939566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201404804
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