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An adaptive permutation approach for genome-wide association study: evaluation and recommendations for use
BACKGROUND: Permutation testing is a robust and popular approach for significance testing in genomic research, which has the broad advantage of estimating significance non-parametrically, thereby safe guarding against inflated type I error rates. However, the computational efficiency remains a chall...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4070098/ https://ncbi.nlm.nih.gov/pubmed/24976866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-7-9 |
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