The expression of apoptosis inducing factor (AIF) is associated with aging-related cell death in the cortex but not in the hippocampus in the TgCRND8 mouse model of Alzheimer’s disease

BACKGROUND: Recent evidence has suggested that Alzheimer’s disease (AD)-associated neuronal loss may occur via the caspase-independent route of programmed cell death (PCD) in addition to caspase-dependent mechanisms. However, the brain region specificity of caspase-independent PCD in AD-associated n...

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Autori principali: Yu, Wenfeng, Bonnet, Mathilde, Farso, Mark, Ma, Keran, Chabot, Jean-Guy, Martin, Elisabeth, Torriglia, Alicia, Guan, Zhizhong, McLaurin, JoAnne, Quirion, Rémi, Krantic, Slavica
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070095/
https://ncbi.nlm.nih.gov/pubmed/24915960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-15-73
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