Features of Large Hinge-Bending Conformational Transitions. Prediction of Closed Structure from Open State

We performed a detailed analysis of conformational transition pathways for a set of 10 proteins, which undergo large hinge-bending-type motions with 4–12 Å RMSD (root mean-square distance) between open and closed crystal structures. Anisotropic network model-Monte Carlo (ANM-MC) algorithm generates...

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Autors principals: Uyar, Arzu, Kantarci-Carsibasi, Nigar, Haliloglu, Turkan, Doruker, Pemra
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2014
Matèries:
Proteins and Nucleic Acids
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070069/
https://ncbi.nlm.nih.gov/pubmed/24940783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.05.017
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