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Direct Observation of T4 Lysozyme Hinge-Bending Motion by Fluorescence Correlation Spectroscopy

Bacteriophage T4 Lysozyme (T4L) catalyzes the hydrolysis of the peptidoglycan layer of the bacterial cell wall late in the infection cycle. It has long been postulated that equilibrium dynamics enable substrate access to the active site located at the interface between the N- and C-terminal domains....

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Autors principals: Yirdaw, Robel B., Mchaourab, Hassane S.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471472/
https://ncbi.nlm.nih.gov/pubmed/23062345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.07.053
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