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Structure based molecular inhibition of Caspase-8 for treatment of multi-neurodegenerative diseases using known natural compounds

Neurodegenerative disorders are often associated with excessive neuronal apoptosis. It is well known that apoptosis is regulated by some intracellular proteases, such as, Caspases (cysteine-dependent, aspartate-specific proteases). In fact, Caspase-8 which is an initiator caspase, has been identifie...

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Main Authors: Ahmad, Khurshid, Khan, Saif, Adil, Mohd, Saeed, Mohd, Srivastava, Ashwini Kumar
Formáid: Artigo
Teanga:Inglês
Foilsithe: Biomedical Informatics 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070048/
https://ncbi.nlm.nih.gov/pubmed/24966519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630010191
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