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Implication of Caspase-3 as a Common Therapeutic Target for Multineurodegenerative Disorders and Its Inhibition Using Nonpeptidyl Natural Compounds

Caspase-3 has been identified as a key mediator of neuronal apoptosis. The present study identifies caspase-3 as a common player involved in the regulation of multineurodegenerative disorders, namely, Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomed Res Int
Hauptverfasser: Khan, Saif, Ahmad, Khurshid, Alshammari, Eyad M. A., Adnan, Mohd, Baig, Mohd Hassan, Lohani, Mohtashim, Somvanshi, Pallavi, Haque, Shafiul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434175/
https://ncbi.nlm.nih.gov/pubmed/26064904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/379817
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