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Structure based molecular inhibition of Caspase-8 for treatment of multi-neurodegenerative diseases using known natural compounds
Neurodegenerative disorders are often associated with excessive neuronal apoptosis. It is well known that apoptosis is regulated by some intracellular proteases, such as, Caspases (cysteine-dependent, aspartate-specific proteases). In fact, Caspase-8 which is an initiator caspase, has been identifie...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biomedical Informatics
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4070048/ https://ncbi.nlm.nih.gov/pubmed/24966519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630010191 |
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