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Polyunsaturated fatty acids inhibit stimulated coupling between the ER Ca(2+) sensor STIM1 and the Ca(2+) channel protein Orai1 in a process that correlates with inhibition of stimulated STIM1 oligomerization
Polyunsaturated fatty acids (PUFAs) have been found to be effective inhibitors of cell signaling in numerous contexts, and we find that acute addition of micromolar PUFAs such as linoleic acid are effective inhibitors of Ca(2+) responses in mast cells stimulated by antigen-mediated crosslinking of F...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4069244/ https://ncbi.nlm.nih.gov/pubmed/24769339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2014.04.006 |
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