Wird geladen...

Molecular anatomy of the early events in STIM1 activation – oligomerization or conformational change?

Decreased luminal endoplasmic reticulum (ER) Ca(2+) concentration triggers oligomerization and clustering of the ER Ca(2+) sensor STIM1 to promote its association with plasma membrane Orai1 Ca(2+) channels leading to increased Ca(2+) influx. A key step in STIM1 activation is the release of its SOAR...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Cell Sci
Hauptverfasser: Korzeniowski, Marek K., Wisniewski, Eva, Baird, Barbara, Holowka, David A., Balla, Tamas
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612226/
https://ncbi.nlm.nih.gov/pubmed/28724757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.205583
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!