Loss of functional NADPH oxidase 2 protects against alcohol-induced bone resorption in female p47phox(-/-) mice

BACKGROUND: In bone, NADPH oxidase (NOX)-derived reactive oxygen species (ROS) superoxide and/or hydrogen peroxide are an important stimulus for osteoclast differentiation and activity. Previously, we have demonstrated that chronic ethanol (EtOH) consumption generates excess NOX-dependent ROS in ost...

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Autors principals: Mercer, Kelly E., Sims, Clark R., Yang, Carrie S., Wynne, Rebecca A., Moutos, Christopher, Hogue, William R., Lumpkin, Charles K., Suva, Larry J., Chen, Jin-Ran, Badger, Thomas M., Ronis, Martin J.J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068959/
https://ncbi.nlm.nih.gov/pubmed/24256560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12305
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