Activated protein C analog with reduced anticoagulant activity improves functional recovery and reduces bleeding risk following controlled cortical impact

The anticoagulant activated protein C (APC) protects neurons and vascular cells from injury through its direct cytoprotective effects that are independent of its anticoagulant action. Wild-type recombinant murine APC (wt-APC) exerts significant neuroprotection in mice if administered early after tra...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Walker, Corey T., Marky, Andrew H., Petraglia, Anthony L., Ali, Tracy, Chow, Nienwen, Zlokovic, Berislav V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068704/
https://ncbi.nlm.nih.gov/pubmed/20513369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.05.075
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