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Metabolic Compensation of Fitness Costs Associated with Overexpression of the Multidrug Efflux Pump MexEF-OprN in Pseudomonas aeruginosa

The acquisition of antibiotic resistance has been associated with a possible nonspecific, metabolic burden that is reflected in decreased fitness among resistant bacteria. We have recently demonstrated that overexpression of the MexEF-OprN multidrug efflux pump does not produce a metabolic burden wh...

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Autori principali: Olivares, Jorge, Álvarez-Ortega, Carolina, Martinez, José Luis
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068598/
https://ncbi.nlm.nih.gov/pubmed/24777101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00121-14
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