Polymorphisms in Pfmdr1, Pfcrt, and Pfnhe1 Genes Are Associated with Reduced In Vitro Activities of Quinine in Plasmodium falciparum Isolates from Western Kenya

In combination with antibiotics, quinine is recommended as the second-line treatment for uncomplicated malaria, an alternative first-line treatment for severe malaria, and for treatment of malaria in the first trimester of pregnancy. Quinine has been shown to have frequent clinical failures, and yet...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Cheruiyot, Jelagat, Ingasia, Luicer A., Omondi, Angela A., Juma, Dennis W., Opot, Benjamin H., Ndegwa, Joseph M., Mativo, Joan, Cheruiyot, Agnes C., Yeda, Redemptah, Okudo, Charles, Muiruri, Peninah, Bidii, Ngalah S., Chebon, Lorna J., Angienda, Paul O., Eyase, Fredrick L., Johnson, Jacob D., Bulimo, Wallace D., Andagalu, Ben, Akala, Hoseah M., Kamau, Edwin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Epidemiology and Surveillance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068580/
https://ncbi.nlm.nih.gov/pubmed/24752268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02472-14
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi