In Vitro and In Vivo Activities of Three Oxazolidinones against Nonreplicating Mycobacterium tuberculosis

Oxazolidinones represent a new class of antituberculosis drugs that exert their function by inhibiting protein synthesis. Here, we compared the activities of three oxazolidinones, linezolid, PNU-100480, and AZD5847, against latent tuberculosis using a simple model employing the streptomycin-starved...

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Autori principali: Zhang, Ming, Sala, Claudia, Dhar, Neeraj, Vocat, Anthony, Sambandamurthy, Vasan K, Sharma, Sreevalli, Marriner, Gwendolyn, Balasubramanian, V., Cole, Stewart T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068502/
https://ncbi.nlm.nih.gov/pubmed/24663022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02410-14
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