Activities of Several Novel Oxazolidinones against Mycobacterium tuberculosis in a Murine Model

The activities of linezolid, eperezolid, and PNU-100480 were evaluated in a murine model of tuberculosis. Approximately 10(7) viable Mycobacterium tuberculosis ATCC 35801 organisms were given intravenously to 4-week-old outbred CD-1 mice. In the first study, treatment was started 1 day postinfection...

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Main Authors: Cynamon, M. H., Klemens, S. P., Sharpe, C. A., Chase, S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC89131/
https://ncbi.nlm.nih.gov/pubmed/10223934
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