Prediction of Substrates for Glutathione Transferases by Covalent Docking

[Image: see text] Enzymes in the glutathione transferase (GST) superfamily catalyze the conjugation of glutathione (GSH) to electrophilic substrates. As a consequence they are involved in a number of key biological processes, including protection of cells against chemical damage, steroid and prostag...

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Bibliographische Detailangaben
Hauptverfasser: Dong, Guang Qiang, Calhoun, Sara, Fan, Hao, Kalyanaraman, Chakrapani, Branch, Megan C., Mashiyama, Susan T., London, Nir, Jacobson, Matthew P., Babbitt, Patricia C., Shoichet, Brian K., Armstrong, Richard N., Sali, Andrej
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068255/
https://ncbi.nlm.nih.gov/pubmed/24802635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci5001554
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