Cannabinoid type 2 receptor stimulation attenuates brain edema by reducing cerebral leukocyte infiltration following subarachnoid hemorrhage in rats

Early brain injury (EBI), following subarachnoid hemorrhage (SAH), comprises blood-brain barrier (BBB) disruption and consequent edema formation. Peripheral leukocytes can infiltrate the injured brain, thereby aggravating BBB leakage and neuroinflammation. Thus, anti-inflammatory pharmacotherapies m...

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Hauptverfasser: Fujii, Mutsumi, Sherchan, Prativa, Krafft, Paul R., Rolland, William B., Soejima, Yoshiteru, Zhang, John H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067767/
https://ncbi.nlm.nih.gov/pubmed/24819918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2014.04.034
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