Inhibition of Rho kinase by Hydroxyfasudil Attenuates Brain Edema after Subarachnoid Hemorrhage in Rats

The blood-brain barrier (BBB) disruption and brain edema are important pathophysiologies of early brain injury after subarachnoid hemorrhage (SAH). This study is to evaluate whether Rho kinase (Rock) enhances BBB permeability via disruption of tight junction proteins during early brain injury. Adult...

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Библиографические подробности
Главные авторы: Fujii, Mutsumi, Duris, Kamil, Altay, Orhan, Soejima, Yoshiteru, Sherchan, Prativa, Zhang, John H.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288616/
https://ncbi.nlm.nih.gov/pubmed/22226843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2011.12.014
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