Inhibition of Rho kinase by Hydroxyfasudil Attenuates Brain Edema after Subarachnoid Hemorrhage in Rats

The blood-brain barrier (BBB) disruption and brain edema are important pathophysiologies of early brain injury after subarachnoid hemorrhage (SAH). This study is to evaluate whether Rho kinase (Rock) enhances BBB permeability via disruption of tight junction proteins during early brain injury. Adult...

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Hauptverfasser: Fujii, Mutsumi, Duris, Kamil, Altay, Orhan, Soejima, Yoshiteru, Sherchan, Prativa, Zhang, John H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288616/
https://ncbi.nlm.nih.gov/pubmed/22226843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2011.12.014
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