Hyperbaric oxygen preconditioning attenuates hyperglycemia-enhanced hemorrhagic transformation by inhibiting matrix metalloproteinases in focal cerebral ischemia in rats

Hyperglycemia dramatically aggravates brain infarct and hemorrhagic transformation (HT) after ischemic stroke. Oxidative stress and matrix metalloproteinases (MMPs) play an important role in the pathophysiology of HT. Hyperbaric oxygen preconditioning (HBO-PC) has been proved to decrease oxidative s...

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Main Authors: Soejima, Yoshiteru, Hu, Qin, Krafft, Paul R., Fujii, Mutsumi, Tang, Jiping, Zhang, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742563/
https://ncbi.nlm.nih.gov/pubmed/23537951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2013.03.019
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