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p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes
The p53 tumor suppressor protein is a major sensor of cellular stresses, and upon stabilization, activates or represses many genes that control cell fate decisions. While the mechanism of p53-mediated transactivation is well established, several mechanisms have been proposed for p53-mediated repress...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4067464/ https://ncbi.nlm.nih.gov/pubmed/24096481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.378 |
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