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Botulinum neurotoxin D-C uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, D-C and G toxins
Botulinum neurotoxins (BoNTs) are classified into seven types (A–G), but multiple subtype and mosaic toxins exist. These subtype and mosaic toxins share a high sequence identity, and presumably the same receptors and substrates with their parental toxins. Here, we report that a mosaic toxin, type D-...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Company of Biologists
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4067266/ https://ncbi.nlm.nih.gov/pubmed/22454523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.103564 |
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