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A Novel Ste20-related Proline/Alanine-rich Kinase (SPAK)-independent Pathway Involving Calcium-binding Protein 39 (Cab39) and Serine Threonine Kinase with No Lysine Member 4 (WNK4) in the Activation of Na-K-Cl Cotransporters

Na(+)-dependent chloride cotransporters (NKCC1, NKCC2, and NCC) are activated by phosphorylation to play critical roles in diverse physiological responses, including renal salt balance, hearing, epithelial fluid secretion, and volume regulation. Serine threonine kinase WNK4 (With No K = lysine membe...

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Detalhes bibliográficos
Main Authors: Ponce-Coria, Jose, Markadieu, Nicolas, Austin, Thomas M., Flammang, Lindsey, Rios, Kerri, Welling, Paul A., Delpire, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067202/
https://ncbi.nlm.nih.gov/pubmed/24811174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.540518
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