Reduction of Proteinuria through Podocyte Alkalinization

Podocytes are highly differentiated cells and critical elements for the filtration barrier of the kidney. Loss of their foot process (FP) architecture (FP effacement) results in urinary protein loss. Here we show a novel role for the neutral amino acid glutamine in structural and functional regulati...

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Main Authors: Altintas, Mehmet M., Moriwaki, Kumiko, Wei, Changli, Möller, Clemens C., Flesche, Jan, Li, Jing, Yaddanapudi, Suma, Faridi, Mohd Hafeez, Gödel, Markus, Huber, Tobias B., Preston, Richard A., Jiang, Jean X., Kerjaschki, Dontscho, Sever, Sanja, Reiser, Jochen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067184/
https://ncbi.nlm.nih.gov/pubmed/24817115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.568998
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