Reduction of Proteinuria through Podocyte Alkalinization

Podocytes are highly differentiated cells and critical elements for the filtration barrier of the kidney. Loss of their foot process (FP) architecture (FP effacement) results in urinary protein loss. Here we show a novel role for the neutral amino acid glutamine in structural and functional regulati...

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Main Authors: Altintas, Mehmet M., Moriwaki, Kumiko, Wei, Changli, Möller, Clemens C., Flesche, Jan, Li, Jing, Yaddanapudi, Suma, Faridi, Mohd Hafeez, Gödel, Markus, Huber, Tobias B., Preston, Richard A., Jiang, Jean X., Kerjaschki, Dontscho, Sever, Sanja, Reiser, Jochen
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2014
主題:
Metabolism
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067184/
https://ncbi.nlm.nih.gov/pubmed/24817115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.568998
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