Reduction of Proteinuria through Podocyte Alkalinization

Podocytes are highly differentiated cells and critical elements for the filtration barrier of the kidney. Loss of their foot process (FP) architecture (FP effacement) results in urinary protein loss. Here we show a novel role for the neutral amino acid glutamine in structural and functional regulati...

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Detalhes bibliográficos
Principais autores: Altintas, Mehmet M., Moriwaki, Kumiko, Wei, Changli, Möller, Clemens C., Flesche, Jan, Li, Jing, Yaddanapudi, Suma, Faridi, Mohd Hafeez, Gödel, Markus, Huber, Tobias B., Preston, Richard A., Jiang, Jean X., Kerjaschki, Dontscho, Sever, Sanja, Reiser, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067184/
https://ncbi.nlm.nih.gov/pubmed/24817115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.568998
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