Low Density Lipoprotein Receptor Class A Repeats Are O-Glycosylated in Linker Regions

The low density lipoprotein receptor (LDLR) is crucial for cholesterol homeostasis and deficiency in LDLR functions cause hypercholesterolemia. LDLR is a type I transmembrane protein that requires O-glycosylation for stable expression at the cell surface. It has previously been suggested that LDLR O...

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Detalhes bibliográficos
Main Authors: Pedersen, Nis Borbye, Wang, Shengjun, Narimatsu, Yoshiki, Yang, Zhang, Halim, Adnan, Schjoldager, Katrine Ter-Borch Gram, Madsen, Thomas Daugbjerg, Seidah, Nabil G., Bennett, Eric Paul, Levery, Steven B., Clausen, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067166/
https://ncbi.nlm.nih.gov/pubmed/24798328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.545053
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