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Mutation analysis of genes in the EGFR pathway in Head and Neck cancer patients: implications for anti-EGFR treatment response

BACKGROUND: Targeted therapy against the Epidermal Growth Factor Receptor (EGFR) is among the most promising molecular therapeutics for Head and Neck Squamous Cell Carcinoma (HNSCC). However, drug resistance limits the clinical efficacy of anti-EGFR monoclonal antibodies and no predictive biomarker...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Boeckx, Carolien, Weyn, Christine, Vanden Bempt, Isabelle, Deschoolmeester, Vanessa, Wouters, An, Specenier, Pol, Van Laer, Carl, Van den Weyngaert, Danielle, Kockx, Mark, Vermorken, Jan B, Peeters, Marc, Pauwels, Patrick, Lardon, Filip, Baay, Marc
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067106/
https://ncbi.nlm.nih.gov/pubmed/24899223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-337
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