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Adjustment for Population Stratification via Principal Components in Association Analysis of Rare Variants
For unrelated samples, principal component (PC) analysis has been established as a simple and effective approach to adjusting for population stratification in association analysis of common variants (CVs, with minor allele frequencies MAF > 5%). However, it is less clear how it would perform in a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4066816/ https://ncbi.nlm.nih.gov/pubmed/23065775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21691 |
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