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Adjusting for Population Stratification in a Fine Scale with Principal Components and Sequencing Data

Population stratification is of primary interest in genetic studies to infer human evolution history and to avoid spurious findings in association testing. Although it is well studied with high-density single nucleotide polymorphisms (SNPs) in genome-wide association studies (GWASs), next-generation...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zhang, Yiwei, Shen, Xiaotong, Pan, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864649/
https://ncbi.nlm.nih.gov/pubmed/24123217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21764
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