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A humanised antibody that regulates the alternative pathway convertase: potential for therapy of renal disease associated with nephritic factors()
Dysregulation of the complement alternative pathway (AP) can cause disease in various organs that may be life-threatening. Severe AP dysregulation can be triggered by autoantibodies to the C3 convertase, termed nephritic factors, which cause pathological stabilisation of the convertase enzyme and co...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4066585/ https://ncbi.nlm.nih.gov/pubmed/24729617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303131 |
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