Notch regulation of myogenic versus endothelial fates of cells that migrate from the somite to the limb

Multipotent Pax3-positive (Pax3(+)) cells in the somites give rise to skeletal muscle and to cells of the vasculature. We had previously proposed that this cell-fate choice depends on the equilibrium between Pax3 and Foxc2 expression. In this study, we report that the Notch pathway promotes vascular...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mayeuf-Louchart, Alicia, Lagha, Mounia, Danckaert, Anne, Rocancourt, Didier, Relaix, Frederic, Vincent, Stéphane D., Buckingham, Margaret
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066530/
https://ncbi.nlm.nih.gov/pubmed/24927569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1407606111
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