Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic program

Pax3/7-dependent stem cells play an essential role in skeletal muscle development. We now show that Fgfr4 lies genetically downstream from Pax3 and is a direct target. In chromatin immunoprecipitation (ChIP)-on-chip experiments, Pax3 binds to a sequence 3′ of the Fgfr4 gene that directs Pax3-depende...

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Библиографические подробности
Главные авторы: Lagha, Mounia, Kormish, Jay D., Rocancourt, Didier, Manceau, Marie, Epstein, Jonathan A., Zaret, Kenneth S., Relaix, Frédéric, Buckingham, Margaret E.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2008
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492669/
https://ncbi.nlm.nih.gov/pubmed/18593883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.477908
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